A variant of Polysporin, called Polysporin Triple Ointment, replaces neomycin with gramicidin, providing an alternative for those allergic to neomycin while still offering broad-spectrum coverage against both Gram-negative and Gram-positive bacteria. Find patient medical information for Neomycin/Polymyxin B/Hydrocortisone otic (Cortisporin Otic, Casporyn HC, Oticair) on WebMD including its uses, side effects and safety, interactions. Triple antibiotic ointments usually combine three active ingredients—neomycin, polymyxin, and bacitracin—to help protect against a broader range of bacteria in minor cuts, scrapes, and burns. Neomycin and polymyxin B sulfates are antibiotics often combined in medications to treat various infections. Understanding their uses, dosages, side effects, and different forms is crucial for safe and effective treatment. Neomycin, polymyxin B, and dexamethasone combination is used to treat eye infections and inflammation, including conjunctivitis and chronic anterior uveitis. It also prevents damage caused by chemicals, radiation, or foreign objects entering the eye. Neomycin, polymyxin B, and hydrocortisone combination ear drops is used to treat infections of the ear canal and to help provide relief from redness, irritation, and discomfort of certain ear problems. Neomycin, Polymyxin, Hydrocortisone Ear Drops package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. NEOMYCIN; POLYMYXIN B; DEXAMETHASONE (nee oh MYE sin; pol i MIX in B; dex a METH a sone) treats eye swelling, redness, or itching caused by infections, injury, or other conditions. It also prevents and treats eye infections caused by bacteria. It works by killing or preventing the growth of bacteria. Breaks down how neomycin and polymyxin work together, common formulations, allergy risks, resistance concerns, and safety considerations for wound and ear care. Neomycin and Polymyxin B Sulfates package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.